分析学科带头人—李峰教授
![](/huayao/eWebEditor/UploadFile/2014331163729875.jpg)
李 峰,男,1970年3月生于山东曲阜,理学博士,教授,博士生导师,享受青岛市政府特贴专家,山东省有突出贡献的中青年专家。1997年7月毕业于中科院长春应化所获理学硕士学位,2005年6月毕业于南开大学获理学博士学位,师从“长江学者”严秀平教授,2009年9月进入山东师范大学化学博士后科研流动站,合作导师唐波教授。1997.7~2013.1期间先后任教于曲阜师范大学和青岛科技大学。现受聘为青岛农业大学化学与药学院教授,分析化学学科带头人。
李峰博士一直从事生物化工、化学生物学等化学与生物、海洋、烟草等交叉领域的科学研究工作,在Anal. Chem., Chem. Commun., Biosens. Bioelectron.等重要学术期刊上发表SCI论文70余篇,其中以第一作者或通信作者发表影响因子3.0以上48篇(5.0以上24篇,6.0以上6篇,引用800余次)。授权国家发明专利7项。作为项目负责人,承担国家自然科学基金3项、中国烟草总公司山东省公司科技计划项目、山东省自然科学基金、药物化学生物学国家重点实验室开放基金、电分析化学国家重点实验室开放基金,中国博士后特别资助、中国博士后基金、山东省博士后创新项目专项资金、青岛市科技计划基础研究项目各1项。作为子课题负责人,承担国家科技支撑计划、海洋公益性行业科研专项经费项目各1项。
荣获山东省自然科学二等奖1项(首位)、第九届山东省青年科技奖、第三届山东省优秀研究生指导教师、青岛市“工人先锋”、山东高等学校优秀科研成果自然科学类一等奖2项(首位)、第二十届全国发明展览会银奖1项(首位)。所指导的研究生2人获山东省优秀硕士学位论文,1人获山东省优秀研究生,1人获山东高等学校优秀科研成果自然科学类一等奖,1人获山东省研究生优秀科技创新成果二等奖。
主要学术论文:
2) Shufeng Liu, Ying Lin, Tao Liu, Chuanbin Cheng, Wenji Wei, Li Wang,
Feng Li*,
Enzyme-free and label-free ultrasensitive electrochemical detection of DNA and adenosine triphosphate by dendritic DNA concatamer-based signal amplification,
Biosensors & Bioelectronics,
2014, 56: 12–18 (SCI 5.437)
4) Ting Hou, Xiaojuan Liu, Xiuzhong Wang, Ai-wen Jiang, Shufeng Liu, Feng Li*, DNAzyme-guided polymerization of aniline for ultrasensitive electrochemical detection of nucleic acid with bio-bar codes-initiated rolling circle amplification, Sensors and Actuators B: Chemical, 2014, 190, 384–388 (SCI 3.535)
5) Shufeng Liu, Jingjing Ming, Ying Lin, Chunfeng Wang, Tao Liu, Chuanbin Cheng, Feng Li*, Amplified detection of T4 polynucleotide kinase activity based on a λ-exonuclease cleavage-induced DNAzyme releasing strategy, Sensors and Actuators B: Chemical, 2014, 192: 157–163 (SCI 3.535)
6) Ting Hou, Xiuzhong Wang, Tingting Lu, Xiaojuan Liu, Feng Li*, Sensitive detection of T4 polynucleotide kinase activity based on coupled exonuclease reaction and nicking enzyme assisted fluorescence signal amplification, Analytical & Bioanalytical Chemistry, 2014, DOI: 10.1007/s00216-014-7719-6 (SCI 3.696)
7) Shufeng Liu, Chengxin Zhang, Jingjing Ming, Chunfeng Wang, Tao Liu, Feng Li*, Amplified detection of DNA by analyte-induced Y-shaped junction probe assembly followed with nicking endonuclease-mediated autocatalytic recycling process, Chemical Communications, 2013, 49(72), 7947–7949 (SCI 6.378)
8) Shufeng Liu, Ying Wang, Chengxin Zhang, Ying Lin, Feng Li*, Homogenous electrochemical aptamer-based ATP assay with signal amplification by exonuclease III assisted target recycling, Chemical Communications, 2013, 49 (23), 2335–2337 (SCI 6.378)
9) Shufeng Liu, Ying Wang, Jingjing Ming, Ying Lin, Chuanbin Cheng, Feng Li*, Enzyme-free and ultrasensitive electrochemical detection of nucleic acids by target catalyzed hairpin assembly followed with hybridization chain reaction, Biosensors & Bioelectronics, 2013, 49, 472–477 (SCI 5.437)
10) Liang Li, Bo Liang,
Feng Li*, Jianguo Shi, Marco Mascini, Qiaolin Lang, Aihua Liu,
Co-immobilization of glucose oxidase and xylose dehydrogenase displayed whole cell on multiwalled carbon nanotube nanocomposite films modified electrode for simultaneous voltammetric detection of D-glucose and D-xylose,
Biosensors & Bioelectronics,
2013, 42, 156–162 (SCI 5.437 )
11)
Feng Li, Limin Yang, Mingqin Chen, Yi Qian, Bo Tang, A novel and versatile sensing platform based on HRP-mimicking DNAzyme-catalyzed template-guided deposition of polyaniline,
Biosensors & Bioelectronics,
2013, 41, 903–906 (SCI 5.437)
12) Feng Li, Zongfeng Du, Limin Yang, Bo Tang, Selective and sensitive turn-on detection of adenosine triphosphate and thrombin based on bifunctional fluorescent oligonucleotide probe, Biosensors & Bioelectronics, 2013, 41, 907–910 (SCI 5.437)
13) Feng Li, Limin Yang, Mingqin Chen, Peng Li, Bo Tang, Selective amperometric sensing platform for lead based on target-induced strand release, Analyst, 2013, 138, 461–466 (SCI 3.969)
14) Ting Hou, Xiuzhong Wang, Xiaojuan Liu, Shufeng Liu, Zongfeng Du, Feng Li*, A label-free and colorimetric turn-on assay for coralyne based on coralyne-induced formation of peroxidase-mimicking split DNAzyme, Analyst 2013, 138(17), 4728–4731 (SCI 3.969)
15) Chunxiang Li, Shuqin Wang, Yangmei Huang, Bin Zheng, Ziqi Tian, Yonghong Wen, Feng Li*, Synthesis, characterization and electrochemiluminescent properties of cyclometalated platinum(II) complexes with substituted 2-phenylpyridine ligands, Dalton Transactions, 2013, 42, 4059–4067 (SCI 3.806)
16) Wenquan Liu, Zongfeng Du, Yi Qian, Feng Li*, A specific colorimetric probe for phosphate detection based on anti-aggregation of gold nanoparticles, Sensors and Actuators B: Chemical, 2013, 176: 927–931 (SCI 3.535)
17) Xiaojuan Liu, Mingqin Chen,Ting Hou, Xiuzhong Wang, Shufeng Liu, Feng Li*, A novel electrochemical biosensor for label-free detection of uracil DNA glycosylase activity based on enzyme–catalyzed removal of uracil bases inducing strand release, Electrochim. Acta, 2013, 113: 514–518 (SCI 3.777)
18) Bo Liang, Liang Li, XiangJiang Tang, Qiaolin Lang, Hongwei Wang, Feng Li, Jianguo Shi, Wei Shen, Ilaria Palchetti, Marco Mascini, Aihua Liu, Microbial surface display of glucose dehydrogenase for amperometric glucose biosensor, Biosen. Bioelectron. 2013, 45, 19–24 (SCI 5.437)
19) Feng Li*, Mingqin Chen, Xinzhi Su, Xiuzhong Wang, Peng Li, A novel graphene oxide-based fluorescence assay for RNA endonuclease activity of mammalian Argonaute2 protein, Sensors and Actuators B: Chemical, 2013, 182, 156–160 (SCI 3.535)
20) XiuZhong Wang, Ting Hou, Wei Li, Mingqin Chen, Feng Li*, Highly sensitive and selective electrochemical identification of D-glucose based on specific Concanavalin A combined with gold nanoparticles signal amplification, Sensors and Actuators B: Chemical 2013, 185, 105–109 (SCI 3.535)
21) Feng Li, Yan Feng, Can Zhao, Peng Li, Bo Tang, A sensitive graphene oxide–DNA based sensing platform for fluorescence “turn-on” detection of bleomycin, Chemical Communications, 2012, 48(1): 127–129 (SCI 6.378)
22) Feng Li, Peng Li, Limin Yang, Bo Tang, Simple and sensitive fluorescence detection of the RNA endonuclease activity of mammalian argonaute2 protein based on RNA molecular beacon, Chemical Communications, 2012, 48 (100), 12192–12194 (SCI 6.378)
23) Shufeng Liu, Zongfeng Du, Peng Li, Feng Li*, Sensitive colorimetric visualization of dihydronicotinamide adenine dinucleotide based on anti-aggregation of gold nanoparticles via boronic acid-diol binding, Biosensors & Bioelectronics, 2012, 35(1): 443–446 (SCI 5.437)
24) Limin Yang, Shufeng Liu, Qixiu Zhang, Feng Li*, Simultaneous electrochemical determination of dopamine and ascorbic acid using AuNPs@polyaniline core–shell nanocomposite modified electrode, Talanta, 2012, 89(1), 136–141 (SCI 3.498)
25) Jingjing Li, Zhen Wang, Peng Li, Nana Zong,
Feng Li*,
A sensitive non-enzyme sensing platform for glucose based on
boronic acid-diol binding,
Sensors and Actuators B: Chemical, 2012, 161(1), 832–837 (SCI 3.535)
26) Feng Li, Yan Feng, Shufeng Liu, Bo Tang, Triggered activity of a nicking endonuclease for mercuric (II) ion-mediated duplex-like DNA cleavage, Chemical Communications, 2011, 47(22): 6347–6349 (SCI 6.378)
27) Feng Li, Yan Feng, Can Zhao, Bo Tang, Crystal violet as a G-quadruplex-selective probe for sensitive amperometric sensing of lead, Chemical Communications, 2011, 47(43): 11909–11911 (SCI 6.378)
28) Feng Li*, Xiaoping Han, Shufeng Liu, Development of an electrochemical DNA biosensor with a high sensitivity of fM by dendritic gold nanostructure modified electrode, Biosensors & Bioelectronics, 2011, 26(5): 2619–2625 (SCI 5.437)
29) Feng Li, Yan Feng, Pingjun Dong, Limin Yang, Bo Tang, Gold nanoparticles modified electrode via simple electrografting of in situ generated mercaptophenyl diazonium cations for development of DNA electrochemical biosensor, Biosensors & Bioelectronics, 2011, 26(5): 1947–1952 (SCI 5.437)
30) Feng Li, Yan Feng, Limin Yang, Liang Li, Chenfei Tang, Bo Tang, A selective novel non-enzyme glucose amperometric biosensor based on lectin–sugar binding on thionine modified electrode, Biosensors & Bioelectronics, 2011, 26(5): 2489–2494 (SCI 5.437)
31) Feng Li, Yan Feng, Can Zhao, Bo Tang, Simple colorimetric sensing of trace bleomycin using unmodified gold nanoparticles, Biosensors & Bioelectronics, 2011, 26(11): 4628–4631 (SCI 5.437)
32) Feng Li*, Jingjing Li, Yan Feng, Limin Yang, Zongfeng Du, Electrochemical behavior of graphene doped carbon paste electrode and its application for sensitive determination of ascorbic acid, Sensors and Actuators B: Chemical, 2011, 157(1): 110–114 (SCI 3.535)
33) Feng Li, Yan Feng, Pingjun Dong, Bo Tang, Gold nanoparticles modified electrode via a mercapto-diazoaminobenzene monolayer and its development in DNA electrochemical biosensor, Biosensors & Bioelectronics, 2010, 25(9): 2084–2088 (SCI 5.437)
34) Feng Li, Yan Feng, Zhen Wang, Limin Yang, Linhai Zhuo, Bo Tang, Direct electrochemistry of horseradish peroxidase immobilized on the layered calcium carbonate–gold nanoparticles inorganic hybrid composite, Biosensors & Bioelectronics, 2010, 25(10): 2244–2248 (SCI 5.437)
35) Xingyong Xu, Yan Feng, Jingjing Li, Feng Li*, Hongjun Yu, A novel protocol for covalent immobilization of thionine on glassy carbon electrode and its application in hydrogen peroxide biosensor, Biosensors & Bioelectronics, 2010, 25(10): 2324–2328 (SCI 5.437)
36) Feng Li*, Yan Feng, Limin Yang, Shufeng Liu, Electrochemical sensing platform based on covalent immobilization of thionine onto gold electrode surface via diazotization–coupling reaction, Talanta, 2010, 83(1): 205–209 (SCI 3.498)
37) Feng Li*, Chenfei Tang, Shufeng Liu, Guangran Ma, Development of an electrochemical ascorbic acid sensor based on the incorporation of a ferricyanide mediator with a polyelectrolyte–calcium carbonate microsphere, Electrochim. Acta, 2010, 55: 838–843 (SCI 3.777)
38) Feng Li*, Wei Chen, Pingjun Dong, Shusheng Zhang, A simple strategy of probe DNA immobilization by diazotization-coupling on self-assembled 4-aminothiophenol for DNA electrochemical biosensor, Biosensors & Bioelectronics, 2009, 24(7): 2160–2164 (SCI 5.437)
39) Feng Li, Zhen Wang, Wei Chen, Shusheng Zhang, A simple strategy for one-step construction of bienzyme biosensor by in-situ formation of biocomposite film through electrodeposition, Biosensors & Bioelectronics, 2009, 24(10): 3030–3035 (SCI 5.437)
40)
Feng Li*, Pingjun Dong, Qianfen Zhuang,
Novel column-based protein refolding strategy using dye-ligand affinity chromatography based on macroporous biomaterial,
J. Chromatogr. A, 2009, 1216(20):4383–4387 (SCI 4.612)
41) Feng Li, Wei Chen, Shusheng Zhang, Development of DNA electrochemical biosensor based on covalent immobilization of probe DNA by direct coupling of sol-gel and self-assembly technologies
Biosensors & Bioelectronics, 2008, 24(4): 781–786 (SCI 5.437)