简历及研究领域：

杨立敏，女，1986年6月生，博士，教授，硕士生导师，邮箱：yanglimin@qau.edu.cn

2012/09--2017/12 山东师范大学 分析化学专业 博士 导师：唐波

2009/09--2012/06 青岛科技大学 分析化学专业 硕士  导师：李峰

2005/09--2009/06 内蒙古师范大学 化学专业   学士

近几年来，本人一直从事功能纳米荧光探针、生物传感器的设计构建与生物应用的研究工作。作为项目负责人，主持承担国家自然科学基金面上项目、国家自然科学基金青年项目等课题。获山东省自然科学二等奖（第四位）2项，获中国分析测试协会科学技术奖（CAIA奖）二等奖（第二位）、山东化学化工学会自然科学奖二等奖（第一位）各1项；以第一或通讯作者在Anal. Chem.、Biosens. Bioelectron.、Chem. Commun.等期刊发表SCI收录论文30余篇。

代表性论文：

1. Limin Yang*, Jingang Zhang, Jing Zhang, Ting Hou, Qian Gao, Xiaojuan Liu, Feng Li*, CRISPR-Based Homogeneous Electrochemical Strategy for Near-Zero Background Detection of Breast Cancer Extracellular Vesicles via Fluidity-Enhanced Magnetic Capture Nanoprobe, Analytical Chemistry, 2025, 97, 2176-2185

2. Limin Yang, Heng Guo, Qian Gao, Ting Hou, Jingang Zhang, Xiaojuan Liu, Feng Li*，Integrating Reliable Pt-S Bond-Mediated 3D DNA Nanomachine with Magnetic Separation in a Homogeneous Electrochemical Strategy for Exosomal MicroRNA Detection with Low Background and High Sensitivity. Analytical Chemistry, 2023, 95, 17834-17842

3. Limin Yang, Heng Guo, Ting Hou, Jingang Zhang, Feng Li*, Metal-mediated Fe3O4@polydopamine-aptamer capture nanoprobe coupling multifunctional MXene@Au@Pt nanozyme for direct and portable photothermal analysis of circulating breast cancer cells, Biosensors and Bioelectronics, 2023, 234, 115346

4. Limin Yang, Heng Guo, Ting Hou, and Feng Li*, Uncovering the Interaction Between Intracellular Telomerase Activity and Hydrogen Peroxide During Cancer Cells Apoptosis Utilizing a Dual-Color Fluorescent Nanoprobe, Analytical Chemistry, 2022, 94, 15162-15169.

5. Limin Yang, Xuehan Yin, Bin An, Feng Li*, Precise Capture and Direct Quantification of Tumor Exosomes via Highly Efficient Dual-Aptamer Recognition-Assisted Ratiometric Immobilization-Free Electrochemical Strategy, Analytical Chemistry, 2021, 93, 1709-1716.

6. Limin Yang, Yuanyuan Chen, Wei Pan, Hongyu Wang, Na Li* Bo Tang*. Visualizing the Conversion Process of Alcohol-Induced Fatty Liver to Steatohepatitis in Vivo with a Fluorescent Nanoprobe. Analytical Chemistry, 2017, 89, 6196-6201.

7. Limin Yang, Yanfei Ren, Wei Pan, ZhengzeYu, Lili Tong, Na Li*, Bo Tang*. Fluorescent Nanocomposite for Visualizing Cross-Talk between MicroRNA-21 and Hydrogen Peroxide in Ischemia-Reperfusion Injury in Live Cells and In Vivo. Analytical Chemistry, 2016, 88, 11886-11891.

8. Limin Yang, Na Li, Wei Pan, Zhengze Yu, Bo Tang*. Real-Time Imaging of Mitochondrial Hydrogen Peroxide and pH Fluctuations in Living Cells Using a Fluorescent Nanosensor. Analytical Chemistry, 2015, 87, 3678-3684.

9. Limin Yang, Xuehan Yin, Panpan Gai, Feng Li*, Label-free homogeneous electrochemical cytosensor for ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures, Chemical Communications, 2020, 56, 3883-3886.

10. Limin Yang, Bin An, Xuehan Yin, Feng Li*, Competitive coordination-based immobilization-free electrochemical biosensor for highly sensitive detection of arsenic(V) using CeO2-DNA nanoprobe, Chemical Communications, 2020, 56, 5311-5314.