惠妮,女,1978年12月生,博士,教授,硕士生导师
所属学科:应用化学
研究方向:纳米材料制备与生化分析及生物传感。
联系方式:13465449851;邮箱: huini1029@163.com
教育及工作经历:
2001年7月-至今,青岛农业大学,教师
2014年9月-2017年6月,青岛科技大学,化学与分子工程学院,获工学博士学位
2008年9月-2011年6月,青岛科技大学,化学与分子工程学院,分析化学专业,获理学硕士学位
1997年9月-2001年6月,山东师范大学,化学系,应用化学专业,获理学学士学位
科研与工作业绩:
围绕“恶性肿瘤早筛早诊”和“农药残留快速检测”等需求,构建高灵敏度、高特异度、高效经济的技术体系,开发了具有完全自主知识产权的检测、筛查、早期诊断技术,发展了超灵敏抗污染的生物传感器,以期解决普通传感器临床应用“卡脖子”问题(生物污染)。主持国家自然基金青年项目1项、山东省自然科学基金面上项目2项、山东省农业重大应用技术创新项目(子课题)1项,横向课题项2项,国家教育部重点实验室开放课题1项,青岛农业大学高层次人才项目1项。此外,作为主要成员参与国家级及其他类型科研项目十余项。基于上述工作,申请发明专利十余项,授权发明专利8项。主持获得山东省化学化工学会科学技术奖三等奖1项、青岛市分析测试学会二等奖1项,并参与获得中国石油和化学工业联合会科技进步三等奖1项。截至目前,已在ACS Appl. Mater. Interfaces、Biosens. Bioelectron.、和J. Mater. Chem. B等SCI收录期刊上以第一作者或通讯作者身份发表学术论文四十余篇,在新型纳米材料与抗污染生物传感器研发方面取得了显著成果。鉴于本人在教学与科研工作中表现突出,入选青岛农业大学首批优秀人才“特支计划”。
近五年代表性成果列表:
(1) Luyu Sun, Yaxuan Zuo, Yunpeng Lu, Jiasheng Wang*, Ni Hui*, An ultrasensitive electrochemical biosensor for ATP detection in human serum based on tetrahedral nanostructured peptides and exonuclease I-assisted signal amplification strategy, Sensors & Actuators: B. Chemical 442 (2025) 138081
(2) Jiasheng Wang, Luyu Sun, Yaxuan Zuo, Ni Hui*, A highly sensitive molecularly-imprinted electrochemical sensor based on a conducting PEDOT/SA hydrogel for the detection of cortisol with exceptional antifouling properties Sensors and Actuators: B. Chemical 426 (2025) 137133
(3) Ningzhen Li,·Zhenteng Zhang, Tingting Tian, Luyu Sun1, Lixiao Xu, Jiasheng*, Wang, Ni Hui*, A double‑conducting polymer nanowire‑based electrochemical aptasensor for highly sensitive and low fouling detection of cortisol in saliva, Microchimica Acta (2024) 191:600
(4) Luyu Sun, Zhenteng Zhang, Jiasheng Wang, Ni Hui*, A dual-mode electrochemical biosensor based on GO-Fe3O4 doped PEDOTnanocomposite for the ultrasensitive assay of microRNA, Bioelectrochemistry (2024)160: 108786
(5) Keke Xu, Jincheng Yang, Liwei Shen, Xinhui Wang, Ni Hui*, Jiasheng Wang*, An antifouling electrochemical biosensor based on chondroitin sulfate‑functionalized polyaniline and DNA‑peptide conjugates for cortisol determination in body fluids, Microchimica Acta 2023, 190: 494.
(6) Ni Hui, Jiasheng Wang, Dongwei Wang, Peipei Wang, Xiliang Luo, Shaoping Lv, An ultrasensitive biosensor for prostate specific antigen detection in complex serum based on functional signal amplifier and designed peptides with both antifouling and recognizing capabilities, Biosensors and Bioelectronics, 2022, 200, 113921.
(7) Yan Zhou, Haitao Lü, Decheng Zhang, Keke Xu, Ni Hui*, Jiasheng Wang*,Electrochemical Biosensors Based on Conducting Polymer Composite and PAMAM dendrimer for the Ultrasensitive Detection of Acetamiprid in Vegetables, Microchemical Journal 2023, 185: 108284.
(8) Yang Lili, Wang H, Lü H, Ni Hui*, Phytic acid doped poly (3, 4-ethylenedioxythiophene) modified with copper nanoparticles for enzymeless amperometric sensing of glucose, Microchimica Acta, 2020, 187(1): 49.
(9) Lili Yang, Hao Wang, Haitao Lü, and Ni Hui*, Phytic Acid Functionalized Antifouling Conducting Polymer Hydrogel for Electrochemical Detection of MicroRNA, Analytica Chimica Acta, 2020,1124:104-112.
(10) Hao Wang, Haitao Lü, Lili Yang, Zhiling Song, Ni Hui*, Glycyrrhiza Polysaccharide Doped the Conducting Polymer PEDOT Hybrid-modified Biosensors for the Ultrasensitive Detection of microRNA, Analytica Chimica Acta, 2020,1139: 155-163.
(11) JiashengWang, DongweiWang, Ni Hui*, A low fouling electrochemical biosensor based on the zwitterionic polypeptide doped conducting polymer PEDOT for breast cancer marker BRCA1 detection, Bioelectrochemistry, 2020, 136: 107595.
(12) Dongwei Wang, Jiasheng Wang, Zhiling Song, Ni Hui*, Highly selective and antifouling electrochemical biosensors for sensitive MicroRNA assaying based on conducting polymer polyaniline functionalized with zwitterionic peptide, Analytical and Bioanalytical Chemistry, 2020, 3-4: 1-11.
(13) Jiasheng Wang, Ni Hui*, Zwitterionic poly(carboxybetaine) functionalized conducting polymer polyaniline nanowires for the electrochemical detection of carcinoembryonic antigen in undiluted blood serum, Bioelectrochemistry, 2019, 125, 90-96.
(14) Jiasheng Wang, Ni Hui*, A nonfouling voltammetric immunosensor for the carcinoembryonic antigen based on the use of polyaniline nanowires wrapped with hyaluronic acid,Microchimica Acta, 2018, 185: 329.
(15) Ni Hui, Xiaotian Sun, Shuyan Niu, Xiliang Luo*, PEGylated polyaniline nanofibers: antifouling and conducting biomaterial for electrochemical DNA sensing, ACS Applied Materials & Interfaces, 2017, 9(3): 2914-2923.
近五年主持科研项目:
(1)山东省自然科学基金面上项目,ZR2022MB069,基于新型导电聚合物水凝胶抗污染生物传感器的构建及应用研究,2023.01-2025.12,10万元,在研,主持
(2)横向课题 基于导电聚合物纳米材料传感技术的农药残留检测装置,2022.12-2025.12,10万元,在研,主持
(3)横向课题 农药残留新技术的开发,2024.3.1-2029.3.1,10万元,在研,主持
(4)国家自然科学基金青年基金项目,21705088,抗污染功能化导电聚合物纳米线的研制及在血清中microRNA检测应用,2018/01-2020/12,25万元,结题,主持
(5)山东省自然科学基金面上项目,ZR2016BM05,基于核壳结构导电聚合物纳米线抗污染传感器的制备及在肿瘤标志物检测中的应用,2016/01-2018/12,15万元,结题,主持
(6)青岛农业大学高层次人才启动基金,电化学法导电聚合物纳米线的研制及在疾病标志物检测中的应用,2017.12.1-2020.12.30,6万元,结题,主持
(7)山东省农业重大应用技术创新项目一项,SD2019NJ001-2,2019年9月-2021年03月,10万元,结题,主持
(8)山东省生化分析重点实验室开放课题,基于导电聚合物纳米线传感器的研制及在疾病标志物检测中的应用,2020.1-2022.1,2万元,结题,主持