化学与药学院制药工程研究生导师李伟娜

个人简介:李伟娜,女,1985年2月10日生,博士研究生/化学博士,副教授。

研究方向:超分子化学与分子组装、有机无机纳米杂化材料、胶体与界面化学、表面润湿性接触角检测新方法

学习工作经历:

2004. 09–2008. 06,西南大学,化学与化工学院应用化学专业,本科

2008. 09–2013. 07,清华大学化学系,博士

2013. 07-2016. 12,青岛农业大学化学与药学院,讲师

2017. 01-至今,青岛农业大学化学与药学院,副教授

科学研究:

科研课题

  1. 国家自然科学基金-青年科学基金,基于胆甾酸骨架构建新一类炔基和叠氮拓扑化学反应体系,21403122,2015.01-2017.12(项目负责人)。
  2. 山东省优秀中青年科学家科研奖励基金,两亲性均聚生物高分子介导的金纳米粒子可控组装,BS2014CL016,2014.09-2016.10(项目负责人)。
  3. 青岛市科技成果转化引导计划(青年专项),胆甾酸主链型高分子与金纳米粒子复合材料的制备、自组装行为及等离子基元特性研究,14-2-4-121-jch,2014.09-2016.09(项目负责人)。
  4. 青岛农业大学高层次人才科研基金,胆甾类生物高分子媒介的纳米粒子可控组装,6631405,2014.03-2017.02(项目负责人)。
  5. 国家自然科学基金-青年科学基金,聚集诱导发光阳离子-核酸免标记复合荧光探针的设计、合成及其在肿瘤标志物中的应用研究,21605093,2017.01-2019.12(参与人2/7)
  6. 国家自然科学基金-青年科学基金,新型自供能细胞传感平台构建及循环肿瘤细胞检测研究,21605092,2017.01-2019.12(参与人3/7)。

发表论文

  1. Jinzhi Sun, Xiang Xu, Guanghui Yu, Weina Li*, Jinsheng Shi*; Coumarin-based tripodal chemosensor for selective detection of Cu(II) ion and resultant complex as anion probe through a Cu(II) displacement approach, Tetrahedron, 2018, 987-991.
  2. Jinzhi Sun, Weina Li*, Lin Xiao, Guanghui Yu, Jinsheng Shi*; Main chain poly(bile acid) directed plasmonic nanospheres with amphiphilic binding pockets and photo-triggered destruction; RSC Advances, 2016, 6, 62200-62207.
  3. Jinzhi Sun, Shuaishuai Xiang, Xiang Xu, Weina Li*, Jinsheng Shi*; Biological deoxycholic acid-coumarin conjugates: photo-switchable structures and self-assembly morphology; Tetrahedron Letters, 2016, 57, 2125-2128.
  4. Weina Li, Yan Li, Xianpeng Yin, Yun Liang, Jian Li, Chen Wang, Yue Lan, Hui Wang, Yong Ju*, Guangtao Li*; Azobenzene-bridged bile acid dimers: an interesting class of conjugates with conformation-controlled bioactivity; Tetrahedron Letters, 2016, 57, 2539-2543.
  5. Weina Li*, Jinzhi Sun, Jinsheng Shi, Shuanghong Hao, Qingzhi Liu, Guanghui Yu; Neutral cholic acid-coumarin conjugate exhibit excellent anion binding properties by cooperative aryl CH and amide NH segments, Supramolecular Chemistry, 2016, 28, 686-692.
  6. Qiaoli Wang, Weina Li*, Jinsheng Shi*; Biomolecule-assisted route for shape-controlled synthesis of 3D flower-like CdWO4 microstructures; RSC Advances, 2015, 5, 61330-61336.
  7. Weina Li, Tian Tian, Yue Lan, Yong Ju* and Guangtao Li*; Self-assembled Main Chain Poly(bile acid)s Membrane that Wrinkle; Polymer Chemistry, 2014, 5, 743-751.
  8. Weina Li, Zuli Wang*; Kumada-Tamao-Corriu Cross-Coupling Reaction of O-based Electrophiles with Grignard Reagents via C-O Bond Activation; RSC Advances, 2013, 3, 25565-25575.
  9. Weina Li, Tian Tian, Wei Zhu, Jiecheng Cui, Yong Ju* and Guangtao Li*; Metal-free click approach for facilely producing main chain poly(bile acid)s; Polymer Chemistry, 2013, 4, 3057-3068.
  10. Weina Li, Qiong Xu, Yan Li, Wei Zhu, Jiecheng Cui, Yong Ju* and Guangtao Li* Bile Acid-based Cyclic Dimers Exhibit Fluoride Coordination by Cooperative Aliphatic and Triazole CH Segments Tetrahedron Letters, 2013, 54, 3868-3871.
  11. Weina Li, Xuesong Li, Wei Zhu, Changxu Li, Dan Xu, Yong Ju* and Guangtao Li* Topochemical approach to efficiently produce main-chain poly(bile acid)s with high molecular weights. Chem. Commun. 2011, 47, 7728

教学授课情况:药用高分子材料,口腔生物材料学,生物功能材料综合实验

指导大学生科技创新项目:

  1. 两亲性均聚生物高分子介导的金纳米粒子可控组装,2014.12-2015.12
  2. 光控可逆生物分子体系的构筑,2016.12-2017.12
  3. 一种构型控制活性的广谱抗菌材料的开发,2016.12-2017.12
  4. 基于反应性接触角变化的有机磷化合物的特异性现场检测新方法,2017.12-2018.12
  5. 具有自适应亲水性和疏水性孔道的金属-有机框架化合物的构筑及其主客体性能研究,2019.4-2020.4